IDOR-1117-2520, CAS 2737274-49-4

Product Description: IDOR-1117-2520 is a potent and selective antagonist of CCR6. IDOR-1117-2520 antagonizes the CCL20-mediated calcium flow (IC50 = 63 nM) and inhibits β-arrestin recruitment to human CCR6 (IC50 = 30 nM) in cells expressing recombinant human CCR6. IDOR-1117-2520 can be used for research of autoimmune diseases[1].

Applications: COVID-19-immunoregulation

Formula: C25H32N4O3

References: [1]Meyer EA, et al. Discovery of the Clinical Candidate IDOR-1117-2520: A Potent and Selective Antagonist of CCR6 for Autoimmune Diseases. J Med Chem. 2024 May 10.

CAS Number: 2737274-49-4

Molecular Weight: 436.55

Compound Purity: 99.94

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: CCR

• Artikelnummer: MEXHY-162495-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-162495-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK