Clone: R508
Specificity: Human IL-6. No cross-reactivity with rat IL6 or mouse IL6 in ELISA assay
Antibody Modification: Preservative Free Unconjugated
Presentation: 0.2 µm filtered solution in PBS
Immunogen: Recombinant Human IL6 / IL-6 protein
Gene: IL6 / Interleukin 6
Description: Interleukin 6 antibody LS-C819031 is an unconjugated rabbit monoclonal antibody to human Interleukin 6 (IL6). Validated for Block, ELISA and Neut.
Usage: Block: In a functional ELISA which immobilized Human IL6R at 2 ug/ml (100 µL/well) in the plate, the Rabbit anti-Human IL6 Monoclonal Antibody can block the binding of 0.2 ug/ml of IL6 to Human IL6R, The EC50 is 0.67 ug/ml. Neutralization: Recombinant Human IL6 stimulates proliferation in the T1165 mouse plasmacytoma cell line in a dose-dependent manner (blank line). Proliferation elicited by 10 ng/mL of Recombinant Human IL6 is neutralized (red line) by increasing concentrations of Human IL6 neutralizing Monoclonal Antibody. The IC50 is typically 20.5-82 ng/mL. Please Note: Optimal concentrations/dilutions should be determined by the end user.
Synonyms: IL6, B-cell stimulatory factor 2, BSF-2, BSF2, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, Interleukin-6, Interleukin BSF-2, IFNB2, B-cell differentiation factor, CDF, HSF, IL-6
Recommended Storage: Store at 2°C to 8°C for up to 1 month. Aliquot and store at -20°C to -80°C for up to 1 year. Avoid freeze/thaw cycles.