Clone Name: DHG-9
Application Note: WB: 1:500-1:2000. ICC/IF: 1:50-1:200. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 127
Form: Liquid
Buffer (with preservative): PBS, 150mM NaCl, 0.04-0.05% BSA, 50% Glycerol, 0.02% Sodium Azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Uniprot ID: P23229
Antigen Species: Human
Immunogen: A synthesized peptide derived from human Integrin alpha 6
Purification: Purified by affinity chromatography
Conjugation: Unconjugated
Full Name: integrin subunit alpha 6
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