Ivosidenib-d5, CAS 2329582-02-5

Product Description: Ivosidenib-d5 (AG-120-d5) is deuterium labeled Ivosidenib. Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme, it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C28H17D5ClF3N6O3

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 2329582-02-5

Molecular Weight: 587.99

Research Area: Cancer;Metabolic Disease

Target: Isotope-Labeled Compounds

• Artikelnummer: MEXHY-18767S3-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-18767S3-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK