KLF10-IN-1, CAS 1197834-98-2

Product Description: KLF10-IN-1 (#48-15) is a KLF10 inhibitor with an IC50 value of 40 μM for KLF10 reporter gene. KLF10-IN-1 can inhibit KLF10-DNA binding and transcriptional activity, block the conversion of CD4+CD25−T cells to CD4+CD25+T regulatory cells, and inhibit the expression of KLF10 target genes. KLF10-IN-1 can be used as a useful mechanistic probe to study KLF10-mediated effects and T regulatory cell biology[1].

Applications: COVID-19-immunoregulation

Formula: C17H16O5

References: [1]Khedkar SA, et al. Discovery of small molecule inhibitors to Krüppel-like factor 10 (KLF10): implications for modulation of T regulatory cell differentiation. J Med Chem. 2015;58(3):1466-1478.

CAS Number: 1197834-98-2

Molecular Weight: 300.31

Compound Purity: 99.84

Research Area: Inflammation/Immunology

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Fluorescent Dye

• Artikelnummer: MEXHY-W181026-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W181026-100
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK