Application Note: WB: 1:2000. ICC/IF: 1:25. IHC-P: 1:50-1:100. FACS: 1:25. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 26
Form: Liquid
Buffer (with preservative): PBS, 0.09% Sodium Azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015]
Uniprot ID: P26715
Antigen Species: Human
Immunogen: KLH conjugated synthetic peptide between 180-206 amino acids from the C-terminal region of human KLRC1.
Purification: Purified by Protein A followed by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: killer cell lectin like receptor C1
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