Product Description: Kushenol C, isolated from the roots of Sophora flavescens, shows anti-Inflammatory and anti-oxidative stress activities. Kushenol C inhibits BACE1 (β-site APP cleaving enzyme 1) with an IC50 of 5.45 μM[1][2].
Applications: Neuroscience-Neurodegeneration
Formula: C25H26O7
References: [1]Cho BO, et al. In vitro Anti-Inflammatory and Anti-Oxidative Stress Activities of Kushenol C Isolated from the Roots of Sophoraflavescens. Molecules. 2020;25(8):1768. Published 2020 Apr 12./[2]Jung HA, et al. Selective inhibition of prenylated flavonoids from Sophora flavescens against BACE1 and cholinesterases. Am J Chin Med. 2010;38(2):415-429.
CAS Number: 99119-73-0
Molecular Weight: 438.47
Compound Purity: 99.58
Research Area: Inflammation/Immunology
Solubility: DMSO : 75 mg/mL (ultrasonic)
Target: Beta-secretase