LD2, CAS 1134334-55-6

Shelf life (days): 1460

Info: A PRMT9 inhibitor (IC50 = 0.9 µM); reduces the proliferation of Rec-1, Raji, UPN1, BL-41, and OCI-Ly3 cells (IC50s = 2.5-5 µM); induces cell cycle arrest at the G2/M phase in THP-1 cells at 2.5 µM; decreases phosphorylated levels of Chk1 and Chk2 in THP-1 cells; decreases tumor volume in combination with an anti-PD-1 antibody in an AML mouse xenograft model at 10 mg/kg twice per day

Formulation: A solid

Formal Name: 4-chloro-8-methoxy-5-methyl-5H-pyrimido[5,4-b]indole

Purity: ≥95%

Formula Markup: C12H10ClN3O

Formula Weight: 247.68012

CAS Number: 1134334-55-6

• Artikelnummer: CAY42447-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 42447-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK