Marein, CAS 535-96-6

Formulation: A crystalline solid

Formal Name: (2E)-3-(3,4-dihydroxyphenyl)-1-[4-(β-D-glucopyranosyloxy)-2,3-dihydroxyphenyl]-2-propen-1-one

Purity: ≥95%

Formula Markup: C21H22O11

Formula Weight: 450,4

Shelf life (days): 1460

CAS Number: 535-96-6

Notes: Marein is a glucoside chalcone that has been found in C. tinctoria and has diverse biological activities, including antioxidant, enzyme inhibitory, antidiabetic, and anti-inflammatory properties.{58297,58298,58299} It scavenges DPPH (Item No. 14805) radicals (IC50 = 48.35 μM) in a cell-free assay and is an inhibitor of EGFR (IC50 = 19.94 μM).{58297,58298} Marein (50 mg/kg) reduces fasting blood glucose and fasting serum levels of insulin, triglycerides, LDL cholesterol, and total cholesterol in diabetic db/db mice.{58299} It also reduces serum and renal IL-6 and chemokine (C-C motif) ligand 2 (CCL2) levels, as well as decreases kidney fibrosis, in db/db mice.

• Artikelnummer: CAY33213-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33213-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK