Product Description: Minalrestat (ARI-509) is a potent and orally active aldose reductase inhibitor. Minalrestat can be used in the research of diabetes[1].
Applications: Metabolism-sugar/lipid metabolism
Formula: C19H11BrF2N2O4
References: [1]Akamine EH, et al. Minalrestat, an aldose reductase inhibitor, corrects the impaired microvascular reactivity in diabetes. J Pharmacol Exp Ther. 2003 Mar;304(3):1236-42. /[2]Cruz JW, et al. Minalrestat and leukocyte migration in diabetes mellitus. Diabetes Metab Res Rev. 2003 May-Jun;19(3):223-31. /[3]Kapor-Drezgic J, et al. Effect of high glucose on mesangial cell protein kinase C-delta and -epsilon is polyol pathway-dependent. J Am Soc Nephrol. 1999 Jun;10(6):1193-203.
CAS Number: 129688-50-2
Molecular Weight: 449.20
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Aldose Reductase
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