Product Description: MK-0674 is a potent, orally bioavailable and selective cathepsin K inhibitor, with an IC50 of 0.4 nM, shows 1156, 1465, 11857 and 243 fold selectivity over Cat B, Cat F, Cat L and Cat S[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C26H27F6N3O2
References: [1]Isabel E, et al. The discovery of MK-0674, an orally bioavailable cathepsin K inhibitor. Bioorg Med Chem Lett. 2010 Feb 1;20(3):887-92.
CAS Number: 887781-62-6
Molecular Weight: 527.50
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Cathepsin