Mouse anti Human CD57

Mouse anti Human CD57, Monoclonal, IgM, Clone: NK-1

Clone: NK-1.

Background: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo- orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl- sphingomyelin was the most effective, followed by palmitoyl- sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

Positive Control: Human lymph node, Tonsil.

Immunogen: Hybridoma produced from mice immunized with human peripheral blood mononuclear cells.

Purification Method: Protein A/G Chromatography.

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide.

References: Abo, T., et al. J. Immuno., 127, 1024 (1984).

UniProt: Q9P2W7.

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

• Artikelnummer: EXAX2781M
• Hersteller: Exalpha Biologicals Inc
• Hersteller Artikelnummer: X2781M
• Verpackungseinheit: 200 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunoprecipitation, Western Blotting, Immunohistochemistry
• Isotyp: IgM
• Wirt: Mouse