Product Description: Naphazoline (Naphthazoline) is a potent α-adrenergic receptor agonist. Naphazoline reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline can be used for non-bacterial conjunctivitis research[1][2].
Applications: COVID-19-immunoregulation
Formula: C14H14N2
References: [1]Quan L, et, al. Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF. Mol Med Rep. 2016 Apr;13(4):3319-25./[2]Yamaguchi I, et, al. Central and peripheral adrenergic mechanisms regulating gastric secretion in the rat. J Pharmacol Exp Ther. 1977 Oct;203(1):125-31.
CAS Number: 835-31-4
Molecular Weight: 210.27
Compound Purity: 99.74
Research Area: Inflammation/Immunology; Cardiovascular Disease; Cancer
Solubility: DMSO : 62.5 mg/mL (ultrasonic)
Target: Adrenergic Receptor;Interleukin Related;TNF Receptor;VEGFR
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