NDR1 Antibody (pSer281+pThr282): ATTO 488

Rabbit Anti-Human NDR1 (pSer281+pThr282) Polyclonal

Target: NDR1 (pSer281+pThr282)

Conjugate: ATTO 488

Product Type: Polyclonal

Immunogen: A phospho-specific peptide corresponding to residues surrounding Ser281 and Thr282 of human NDR1 (AA278-285)

Swiss-Prot: Q15208

Purification: Peptide Affinity Purified

Storage Buffer: 640.91mM DMSO, 136.36mM Ethanolamine, and 9.09mM Sodium Bicarbonate in 90.9% PBS

Specificity: Detects 54.19 kDa.

Cellular Localization: Nucleus / Cytoplasm

Tissue Specificity: Ubiquitously expressed with highest levels observed in peripheral blood leukocytes.

Scientific Background: STK38 is a negative regulator of MAP3K1/2 signalling. Converts MAP3K2 from its phosphorylated form to its nonphosphorylated form and inhibits autophosphorylation of MAP3K2. The MAPK/ERK pathway has been implicated in oncogenesis as either a promoter or inhibitor depending on the cancer system. Thus, the role of STK38 in cancer is likely highly contextual.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSPC-1035D-A488
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SPC-1035D-A488
• Verpackungseinheit: 100 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Immunohistochemistry, Immunocytochemistry
• Human Gene ID: 11329
• Wirt: Rabbit
• Konjugat: Conjugated, Atto 488