Application Note: WB: 1-3μg/ml. IHC-P: 5-10μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 328
Positive Control: The peptide used to generate this antibody is available for purchase (GTX89207-PEP).
Specificity/Sensitivity: This antibody is expected to recognise isoform 1 (NP_056493.3) and isoform 2 (NP_001191126.1).
Form: Liquid
Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.[provided by RefSeq, Feb 2011]
Uniprot ID: Q8NFP9
Antigen Species: Human
Immunogen: Peptide with sequence C-DFNRWHYEHQNRY, from the C Terminus of the protein sequence according to NP_056493.3; NP_001191126.1.
Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation: Unconjugated
Full Name: neurobeachin
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