Product Description: Nitecapone (OR-462) is an orally active and short-acting catechol-O-methyltransferase (COMT) inhibitor with gastroprotective and antioxidant properties. Nitecapone (OR-462) scavenges reactive oxygen and nitric radicals and prevents lipid peroxidation[1][2][3].
Applications: COVID-19-immunoregulation
Formula: C12H11NO6
References: [1]Y J Suzuki, et al. Antioxidant properties of nitecapone (OR-462). Free Radic Biol Med. 1992 Nov;13(5):517-25./[2]Marcocci L, et al. Nitecapone: a nitric oxide radical scavenger. Biochemistry and Molecular Biology International, 01 Oct 1994, 34(3):531-541./[3]Oleg Kambur, et al. Nitecapone reduces development and symptoms of neuropathic pain after spinal nerve ligation in rats. Eur J Pain. 2011 Aug;15(7):732-40.
CAS Number: 116313-94-1
Molecular Weight: 265.22
Compound Purity: 99.53
Research Area: Inflammation/Immunology; Neurological Disease
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: COMT
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