Target Synonym: NME;Metastasis Inhibition Factor nm;NM23-H;NME1;AWD;GAAD;NB;NBS;NDKA;NDPK-A;NDPKA;NM23;NM23-H1;Granzyme A-Activated DNase;Metastasis Inhibition Factor nm23;NDK A;NDP Kinase A;Nucleoside Diphosphate Kinase A;Tumor Metastatic Process-Associated Protein;drosophila;Granzyme A activated DNase;GZMA activated DNase;homolog 1;homolog of;included;NM23 long variant;NM23H1B;NM23-M1;NME/NM23 nucleoside diphosphate kinase 1;NME1-NME2 spliced read-through transcript;Nonmetastatic cells 1;Non-metastatic cells 1;Nonmetastatic protein 23;protein (NM23A) expressed in;protein expressed in
Background: This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME1), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Immunogen: Recombinant Human NME1 / NDKA protein
Buffer: 0.2 μm filtered solution in 20 mM MES, 100 mM NaCl, 10% Trehalose, 0.02% Tween 80, pH 6.0
Dilution: ICC/IF 1:20-1:100;FCM 1:25-1:100;
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