Shelf life (days): 1460
Info: A K2P2.1/TREK-1 and K2P10.1/TREK-2 activator; induces K2P2.1/TREK-1 and K2P10.1/TREK-2 activity in thallium flux assays using CHO cells expressing K2P2.1/TREK-1 and HEK293 cells expressing K2P10.1/TREK-2 (EC50s = 2.8 and 0.3 µM, respectively); selective for K2P2.1/TREK-1 and K2P10.1/TREK-2 over 72 other ion channels, GPCRs, transporters, and nuclear hormones at 10 µM; prevents acetic acid-induced writhing in mice at 3 mg/kg
Formulation: A neat solid
Formal Name: N-[[2-fluoro-4-(trifluoromethoxy)phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-6-carboxamide
Purity: ≥98%
Formula Markup: C15H10F4N4O2
Formula Weight: 354.264613
CAS Number: 2230296-66-7