OSW-1, CAS 145075-81-6

Product Description: OSW-1, isolated from Ornithogalum caudatum, is a specific antagonist of ooxysterol binding protein (OSBP) and OSBP-related protein 4 (ORP4) with GI50s in the nanomolar range in human cancer lines.

Applications: Cancer-programmed cell death

Formula: C47H68O15

References: [1]Burgett AW, et al. Natural products reveal cancer cell dependence onoxysterol-binding proteins.Nat Chem Biol. 2011 Aug 7;7(9):639-47./[2]Zhang Y, et al, Effective cytotoxic activity of OSW-1 on colon cancer by inducing apoptosis in vitro and in vivo.Oncol Rep. 2017 Jun;37(6):3509-3519.

CAS Number: 145075-81-6

Molecular Weight: 873.03

Compound Purity: 99.66

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Oxysterol-binding Protein-related Protein (ORP)

• Artikelnummer: MEXHY-101213-500UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-101213-500UG
• Verpackungseinheit: 500 μg
• Mengeneinheit: STK