Application Note: WB: 0.3-1μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 100
Positive Control: The peptide used to generate this antibody is available for purchase (GTX89598-PEP).
Specificity/Sensitivity: This antibody is expected to recognise reported isoforms NP_001074.2, NP_236914.2 and NP_246273.2.
Form: Liquid
Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Uniprot ID: O76074
Antigen Species: Human
Immunogen: Peptide with sequence C-LINGESGQAKRN, from the C Terminus of the protein sequence according to NP_001074.2; NP_246273.2; NP_236914.2; (NP_237223).
Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation: Unconjugated
Full Name: phosphodiesterase 5A
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