PE-conjugated Anti-BCMA bispecific antibody(DM4)

Background: BiTE bispecific antibody is an Engineered fusion protein constructed from two single-chain variable fragments (scFvs) of different monoclonal antibodies. One of the scFvs will be constructed from an anti-CD3 monoclonal antibody; and the other scFv fragment which linked by a linker region will be made from an anti-Tumor cell specific monoclonal antibody.The B-cell maturation protein (BCMA or BCM) is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes; and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily; member 13b (TNFSF13B:TALL-1:BAFF); and to lead to NF-kappaB and MAPK8:JNK activation. This receptor also binds to various TRAF family members; and thus may transduce signals for cell survival and proliferation. [provided by RefSeq; Jul 2008]

Description: PE-conjugated Anti-BCMA bispecific antibody(DM4)

Storage & Shipping: Store at 2°C-8°C for 6 months

Formulation & Reconstitution: Liquid，PBS with 0.05% Proclin300, 189% BSA

Target: BCMA

Uniprot ID: Q02223

Usage: Research use only

Clone ID: DM4

Purification: Purified from cell culture supernatant by affinity chromatography

Recommended Dilutions: Flow Cyt 1:100

• Artikelnummer: DMADMB100003P-100
• Hersteller: DIMA Biotechnology
• Hersteller Artikelnummer: DMB100003P-100
• Verpackungseinheit: 100 test
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Flow Cytometry
• Isotyp: Rabbit scfv
• Wirt: Rabbit
• Konjugat: Conjugated, PE (Phycoerythrin)