PE-conjugated Anti-CD117 antibody(DMC446), IgG1 Chimeric mAb

PE-conjugated Anti-CD117 antibody(DMC446), IgG1 Chimeric mAb
Artikelnummer
DMADMC100446P-100
Verpackungseinheit
100 test
Hersteller
DIMA Biotechnology

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Background: This gene encodes a receptor tyrosine kinase. This gene was initially identified as a homolog of the feline sarcoma viral oncogene v-kit and is often referred to as proto-oncogene c-Kit. The canonical form of this glycosylated transmembrane protein has an N-terminal extracellular region with five immunoglobulin-like domains; a transmembrane region; and an intracellular tyrosine kinase domain at the C-terminus. Upon activation by its cytokine ligand; stem cell factor (SCF); this protein phosphorylates multiple intracellular proteins that play a role in in the proliferation; differentiation; migration and apoptosis of many cell types and thereby plays an important role in hematopoiesis; stem cell maintenance; gametogenesis; melanogenesis; and in mast cell development; migration and function. This protein can be a membrane-bound or soluble protein. Mutations in this gene are associated with gastrointestinal stromal tumors; mast cell disease; acute myelogenous leukemia; and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Description: PE-conjugated Anti-CD117 antibody(DMC446), IgG1 Chimeric mAb

Storage & Shipping: Store at 2°C-8°C for 6 months

Formulation & Reconstitution: Liquid,PBS with 0.05% Proclin300, 252% BSA

Target: CD117

Uniprot ID: P10721

Usage: Research use only

Clone ID: DMC446

Purification: Purified from cell culture supernatant by affinity chromatography

Recommended Dilutions: Flow Cyt 1:100
Mehr Informationen
Artikelnummer DMADMC100446P-100
Hersteller DIMA Biotechnology
Hersteller Artikelnummer DMC100446P-100
Verpackungseinheit 100 test
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Flow Cytometry
Isotyp Rabbit/Human Fc chimeric IgG1
Wirt Rabbit
Konjugat Conjugated, PE (Phycoerythrin)
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