PE-conjugated Anti-CD142 antibody(DMC463); IgG1 Chimeric mAb

PE-conjugated Anti-CD142 antibody(DMC463); IgG1 Chimeric mAb
Artikelnummer
DMADMC100463P-100
Verpackungseinheit
100 test
Hersteller
DIMA Biotechnology

Verfügbarkeit: wird geladen...
Preis wird geladen...
Background: This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades; and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades; which circulate as nonfunctional precursors; this factor is a potent initiator that is fully functional when expressed on cell surfaces; for example; on monocytes. There are 3 distinct domains of this factor: extracellular; transmembrane; and cytoplasmic. Platelets and monocytes have been shown to express this coagulation factor under procoagulatory and proinflammatory stimuli; and a major role in HIV-associated coagulopathy has been described. Platelet-dependent monocyte expression of coagulation factor III has been described to be associated with Coronavirus Disease 2019 (COVID-19) severity and mortality. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq; Aug 2020]

Description: PE-conjugated Anti-CD142 antibody(DMC463); IgG1 Chimeric mAb

Storage & Shipping: Store at 2°C-8°C for 6 months

Formulation & Reconstitution: Liquid,PBS with 0.05% Proclin300, 257% BSA

Target: CD142

Uniprot ID: P13726

Usage: Research use only

Clone ID: DMC463

Purification: Purified from cell culture supernatant by affinity chromatography

Recommended Dilutions: Flow Cyt 1:100
Mehr Informationen
Artikelnummer DMADMC100463P-100
Hersteller DIMA Biotechnology
Hersteller Artikelnummer DMC100463P-100
Verpackungseinheit 100 test
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Flow Cytometry
Isotyp Rabbit/Human Fc chimeric IgG1
Wirt Rabbit
Konjugat Conjugated, PE (Phycoerythrin)
Produktinformation (PDF) Download
MSDS (PDF) Download