PE-conjugated Anti-FLT3 antibody(19A5), IgG1 Chimeric mAb

PE-conjugated Anti-FLT3 antibody(19A5), IgG1 Chimeric mAb
Artikelnummer
DMADMC101110P-100
Verpackungseinheit
100 test
Hersteller
DIMA Biotechnology

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Background: Flt-3(Receptor-type tyrosine-protein kinase FLT3) is also known as FLK-2(Fetal liver kinase-2), STK-1(Stem cell tyrosine kinase 1), CD135. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.

Description: PE-conjugated Anti-FLT3 antibody(19A5), IgG1 Chimeric mAb

Storage & Shipping: Store at 2°C-8°C for 6 months

Formulation & Reconstitution: Liquid,PBS with 0.05% Proclin300, 363% BSA

Target: FLT3

Uniprot ID: P36888

Usage: Research use only

Clone ID: 19A5

Purification: Purified from cell culture supernatant by affinity chromatography

Recommended Dilutions: Flow Cyt 1:100
Mehr Informationen
Artikelnummer DMADMC101110P-100
Hersteller DIMA Biotechnology
Hersteller Artikelnummer DMC101110P-100
Verpackungseinheit 100 test
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Flow Cytometry
Isotyp Rabbit/Human Fc chimeric IgG1
Wirt Rabbit
Konjugat Conjugated, PE (Phycoerythrin)
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