Background: This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]
Description: PE-conjugated Anti-FZD4 antibody(10E10), IgG1 Chimeric mAb
Storage & Shipping: Store at 2°C-8°C for 6 months
Formulation & Reconstitution: Liquid，PBS with 0.05% Proclin300, 361% BSA
Target: FZD4
Uniprot ID: Q9ULV1
Usage: Research use only
Clone ID: 10E10
Purification: Purified from cell culture supernatant by affinity chromatography
Recommended Dilutions: Flow Cyt 1:100
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