PERK-IN-5, CAS 2616821-91-9

Product Description: PERK-IN-5 is a highly potent, selectively and orally bioavailable PERK inhibitor (IC50s of 2 and 9 nM for PERK and p-eIF2α, respectively). PERK-IN-5 can significantly inhibit tumor growth in the 786-O renal cell carcinoma xenograft tumor model[1].

Applications: Cancer-Kinase/protease

Formula: C25H26F2N4O3

References: [1]Calvo V, et al. Discovery of 2-amino-3-amido-5-aryl-pyridines as highly potent, orally bioavailable, and efficacious PERK kinase inhibitors. Bioorg Med Chem Lett. 2021;43:128058.

CAS Number: 2616821-91-9

Molecular Weight: 468.50

Compound Purity: 99.40

Research Area: Cancer

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: PERK

• Artikelnummer: MEXHY-145835-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-145835-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK