Product Description: PF-06767832 is a potent muscarinic M1 selective positive allosteric modulator (PAM), with the EC50 of 60 nM. PF-06767832 has good brain penetration[1].
Formula: C22H23N3O3S
References: [1]Jennifer E Davoren, et al. Discovery of the Potent and Selective M1 PAM-Agonist N-[(3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects. J Med Chem. 2016 Jul 14;59(13):6313-28.
CAS Number: 1859081-58-5
Molecular Weight: 409.50
Research Area: Neurological Disease
Target: mAChR