PL 7 Protein

Description of Target: Threonyl-tRNA Synthetase is a member of the aminoacyl-tRNA synthetase family, key enzymes of protein biosynthesis which charge tRNA molecules with the respective amino acids. This 83 kDa protein is an autoantigen recognized by PL-7 antibodies which occur in a subset of patients with polymyositis and dermatomyositis. Preliminary data suggest that PL-7 antibodies (similar to Jo-1 antibodies) indicate an increased risk for lung involvement, but this needs to be confirmed for a larger number of cases. TARS Human Recombinant produced in SF9 is a glycosylated, polypeptide chain.

Molecular Weight: 83 kDa.

Product Format: Liquid 20mM HEPES buffer (pH 8), 200mM sodium chloride, 20% glycerol.

Protein Name: Threonine--tRNA ligase, cytoplasmic.

Purification: Purified by proprietary chromatographic techniques.

Purity: Greater than 90% as determined by SDS-PAGE.

Tag: 6x-His tag

• Artikelnummer: AVIOPPA00824-20
• Hersteller: Aviva Systems Biology
• Hersteller Artikelnummer: OPPA00824-20
• Verpackungseinheit: 20µg
• Mengeneinheit: STK
• Methode: Western Blotting
• Human Gene ID: 6897
• Wirt: Various hosts