PMX 53 acetate(219639-75-5 free base), CAS 852629-88-0

Description: PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an agonist of Mas-related gene 2 (MrgX2).

CAS Number: 852629-88-0

Formula: C49H69N11O9

Molecular Weight: 956,16

References: Subramanian H, et al. PMX-53 as a dual CD88 antagonist and an agonist for Mas-related gene 2 (MrgX2) in human mast cells. Mol Pharmacol. 2011 Jun;79(6):1005-13.

• Artikelnummer: TGMTP2334-200mg
• Hersteller: TargetMol Chemicals
• Hersteller Artikelnummer: TP2334-200mg
• Verpackungseinheit: 200 mg
• Mengeneinheit: STK