PMX 53 (monoacetate), CAS 852629-88-0

Product Description: PMX 53 monoacetate (3D53 monoacetate) is a potent orally active CD88 (C5aR) antagonist that inhibits C5a-induced neutrophil myeloperoxide release and chemotactic activity. PMX 53 monoacetate has an IC50 value of 20 nM against C5a-induced neutrophil myeloperoxide release. >The value is 22 nM, and the IC50 value of the chemotactic activity is 75 nM. PMX 53 monoacetate is also an agonist of MrgX2[1].

Applications: COVID-19-immunoregulation

Formula: C49H69N11O9

References: [1]PMX-53 as a dual CD88 antagonist and an agonist for Mas-related gene 2 (MrgX2) in human mast cells

CAS Number: 852629-88-0

Molecular Weight: 956.14

Research Area: Inflammation/Immunology

Target: Endogenous Metabolite

• Artikelnummer: MEXHY-106178D-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-106178D-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK