Product Description: Prostratin, a natural terpenoid compound, is a PKC activator, with a Ki of 12.5 nM and shows inhibitory effect on HIV-1.
Applications: COVID-19-anti-virus
Formula: C22H30O6
References: [1]Gustafson KR, et al. A nonpromoting phorbol from the samoan medicinal plant Homalanthus nutans inhibits cell killing by HIV-1. J Med Chem. 1992 May 29;35(11):1978-86./[2]Shen X, et al. The protein kinase C agonist prostratin induces differentiation of human myeloid leukemia cells and enhances cellular differentiation by chemotherapeutic agents. Cancer Lett. 2015 Jan 28;356(2 Pt B):686-96./[3]Wang H, et al. Protein kinase D3 is essential for prostratin-activated transcription of integrated HIV-1 provirus promoter via NF-κB signaling pathway. Biomed Res Int. 2014;2014:968027.
CAS Number: 60857-08-1
Molecular Weight: 390.47
Compound Purity: 99.80
Research Area: Cancer; Infection
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: HIV;PKC
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