PRTFDC1 Monoclonal Antibody

Target Synonym: PRTFDC;HHGP;PRTFDC1

Background: PRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG island leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis. PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse and has important implications for unraveling the molecular etiology of lesch-Nyhan disease(LND). LND is a severe X-linked neurological disorder caused by a deficiency of hypoxanthine phosphoribosyltransferase. PRTFDC1 has a low, barely measurable phosphoribosyltransferase activity (in vitro).

Immunogen: Recombinant Human PRTFDC1 protein

Buffer: 0.2 μm filtered solution in PBS

Dilution: WB 1:500-1:1000;

Calculated MW: 28 kDa

Observed MW: 28 kDa

• Artikelnummer: ELSAN200139P-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: AN200139P-100
• Verpackungseinheit: 100μL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Western Blotting
• Isotyp: IgG1
• Wirt: Mouse
• Konjugat: Unconjugated