Target Synonym: CXCL;SCYB;TPAR;C-X-C Motif Chemokine;Stromal Cell-Derived Factor;hSDF;SDF;CXCL12;IRH;PBSF;SCYB12;SDF1;TLSF;TPAR1;hIRH;C-X-C Motif Chemokine 12;hSDF-1;Intercrine Reduced in Hepatomas;Pre-B Cell Growth-Stimulating Factor;SDF-1;Stromal Cell-Derived Factor 1;SDF1A;SDF1B;12-O-tetradecanoylphorbol 13-acetate repressed protein 1;AI174028;Chemokine (C-X-C motif) ligand 12;Chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1);Chemokine CXC motif ligand 12;OTTHUMP00000019491;SDF 1;SDF-1a;SDF-1-alpha(3-67);SDF-1b;Stromal cell-derived factor 1 delta;Stromal cell-derived factor 1 gamma;Stromal cell-derived factor 1a;Stromal cell-derived factor-1 alpha;Thymic lymphoma cell-stimulating factor;Tlsfa;TLSF-a;Tlsfb;TLSF-b
Background: This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to Human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen: Recombinant Human CXCL12 protein
Buffer: PBS, pH 7.2. Contains 0.05% proclin 300.
Dilution: FCM 2 μg/mL(1×105-5×105 cells)
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