Rabbit anti-SMN1 Antibody Affinity Purified

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein Ref Seq ID: NP_000335.1

Uniprot ID: Q16637

Background: Survival motor neuron protein (SMN1) has been identified as the gene that is defective in spinal muscular atrophy (SMA), a neurodegenerative autosomal recessive disease characterized by paralysis and muscular atrophy which results from the loss of motor neurons in the spinal cord. There are two closely related SMN genes that do not appear to be functionally redundant. SMN1 represents the telomeric copy while SMN2 represents the centromeric copy. In the cell, SMN1 is part of a large complex of proteins involved in snRNP biogenesis. The functional role of SMN1 is proposed to play a role in messenger and ribosomal RNA transcription and processing.

Immunogen: Between 244 and C-terminus

Physical State: Liquid

Formulation: BSA-Free

Purity: Antigen Affinity Purified

Antibody Registry ID: AB_1309810

• Artikelnummer: BEYA301-863A-T
• Hersteller: Bethyl Laboratories
• Hersteller Artikelnummer: A301-863A-T
• Verpackungseinheit: 10 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Immunoprecipitation, Western Blotting
• Isotyp: IgG
• Human Gene ID: 6606
• Wirt: Rabbit
• Konjugat: Unconjugated