Product Description: Rec 15/2615 hydrochloride is a potent and selective α-1B adrenoceptor antagonist with Ki values of 1.9 nM, 0.3 nM, 2.6 nM for α1A, α1B, α1D, respectively. Rec 15/2615 hydrochloride modulates vaginal smooth muscle contractility and genital engorgement[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C26H34ClN5O5
References: [1]Bremner JB, et al. Ligand design for alpha1 adrenoceptor subtype selective antagonists. Bioorg Med Chem. 2000 Jan;8(1):201-14. /[2]Kim NN, et al. Biochemical and functional characterization of alpha-adrenergic receptors in the rabbit vagina. Life Sci. 2002 Nov 1;71(24):2909-20.
CAS Number: 173059-17-1
Molecular Weight: 532.03
Research Area: Endocrinology; Cardiovascular Disease
Solubility: 10 mM in DMSO
Target: Adrenergic Receptor