Recombinant Human BAG3 protein (GST tag)

Protein Tag: N-GST

Uniprot: O95817

Accession: O95817

Background: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.

Bio Acitivity: Not validated for activity

Sequence: Gly 421-Ala 498

Purity: > 95% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 10 EU/mg of the protein as determined by the LAL method.

Calculated MW: 33.5 kDa

Observed MW: 35 kDa

• Artikelnummer: ELSPDEH100827-1
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: PDEH100827-1
• Verpackungseinheit: 1mg
• Mengeneinheit: STK
• Reaktivität: Human
• Wirt: Escherichia Coli