Recombinant Human GSTAL Protein(Trx Tag)

Protein Tag: N-Trx

Uniprot: P08263

Accession: P08263

Background: GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adenocarcinoma (Caco-2) cells in culture undergo spontaneous differentiation into mature enterocytes in association with progressive increases in expression of glutathione S-transferase alpha-1 (GSTA1). GSTA1 levels may play a role in modulating enterocyte proliferation but do not influence differentiation or apoptosis. GSTA1 may play a key role during pregnancy.

Bio Acitivity: Not validated for activity

Sequence: Met1-Phe222

Purity: > 95% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin: < 10 EU/mg of the protein as determined by the LAL method

Calculated MW: 44.4 kDa

Observed MW: 39 kDa

• Artikelnummer: ELSPDEH100656-1
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: PDEH100656-1
• Verpackungseinheit: 1mg
• Mengeneinheit: STK
• Reaktivität: Human
• Wirt: Escherichia Coli