Rotigaptide (Standard), CAS 355151-12-1

Product Description: Rotigaptide (Standard) is the analytical standard of Rotigaptide. This product is intended for research and analytical applications. Rotigaptide (ZP123) is a novel and specific modulator of connexin 43 (Cx43). Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress. Rotigaptide is a potent antiarrhythmic peptide (AAP) with improved stability and has the potential for the investigation of cardiac arrhythmias-specifically?atrial fibrillation[1][2].

Formula: C28H39N7O9

References: [1]Seyed Mojtaba Ghiasi, et al. The connexin 43 regulator Rotigaptide reduces cytokine-induced cell death in human islets/[2]Stahlhut M, et al. The antiarrhythmic peptide rotigaptide (ZP123) increases connexin 43 protein expression in neonatal rat ventricular cardiomyocytes.Cell Commun Adhes. 2006 Jan-Apr;13(1-2):21-7./[3]Kjølbye AL, et al. Pharmacological modulation of gap junction function with the novel compound rotigaptide: a promising new principle for prevention of arrhythmias.Basic Clin Pharmacol Toxicol. 2007 Oct;101(4):215-30.

CAS Number: 355151-12-1

Molecular Weight: 617.65

Research Area: Cardiovascular Disease

Target: Gap Junction Protein;Reference Standards

• Artikelnummer: MEXHY-106225R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-106225R-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK