RPR107393 free base, CAS 197576-78-6

Product Description: RPR107393 free base is a selective squalene synthase inhibitor, which inhibits rat liver microsomal squalene synthase with an IC50 of 0.8 nM.

Applications: Metabolism-sugar/lipid metabolism

Formula: C22H22N2O

References: [1]Amin D, et al. RPR107393, a potent squalene synthase inhibitor and orally effective Cholesterol-lowering agent: comparison with inhibitors of HMG-CoA reductase. J Pharmacol Exp Ther. 1997 May;281(2):746-52./[2]Hiyoshi H, et al. Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes. J Lipid Res. 2003 Jan;44(1):128-35.

CAS Number: 197576-78-6

Molecular Weight: 330.42

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Farnesyl Transferase

• Artikelnummer: MEXHY-100299-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-100299-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK