Product Type: Inhibitor
CAS No.: 459868-92-9
MolecularFormula: C19H18FN3O * H3PO4
Molecular Weight: 421,4
Source: Synthetic
Purity: >98% (HPLC); NMR (Conforms)
Solubility: May be dissolved in DMSO (25 mg/ml)
Appearance: Yellow powder
PubChem CID: 9931953
Scientific Background: Rucaparib is a PARP1, PARP2 and PARP3 inhibitor and inhibits PARP-mediated DNA repair (1). It is being developed for ovarian, prostate and bladder cancers (2, 3).
References: 1. https://pubchem.ncbi.nlm.nih.gov/compound/rucaparib 2. Dockery L.E., Gunderson C.C., and Moore K.N. (2017) Onco Target Ther. 10: 3029-3037. 3. Syed Y.Y. (2017) Drugs. 77(5): 585-592.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.