Sarizotan (dihydrochloride), CAS 177976-12-4

Product Description: Sarizotan dihydrochloride (EMD 128130) is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist. Sarizotan (EMD 128130) exhibits IC50 values of 6.5 nM (rat 5-HT1A), 0.1 nM (human 5-HT1A), 15.1 nM (rat D2), 17 nM (human D2), 6.8 nM (human D3) and 2.4 nM (human D4.2), respectively[1].

Formula: C22H23Cl2FN2O

References: [1]G D Bartoszyk, et al. Sarizotan, a Serotonin 5-HT1A Receptor Agonist and Dopamine Receptor Ligand. J Neural Transm (Vienna). 2004 Feb;111(2):113-26./[2]C Marin, et al. Local Administration of Sarizotan Into the Subthalamic Nucleus Attenuates Levodopa-Induced Dyskinesias in 6-OHDA-lesioned Rats. Psychopharmacology (Berl). 2009 Jun;204(2):241-50.

CAS Number: 177976-12-4

Molecular Weight: 421.34

Research Area: Neurological Disease

Target: 5-HT Receptor;Dopamine Receptor

• Artikelnummer: MEXHY-100820B-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-100820B-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK