Product Description: Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.
Applications: Metabolism-sugar/lipid metabolism
Formula: C50H56MgN2O8S2
Citations: BMC Complement Med Ther. 2021 Apr 10;21(1):118./Patent. US20210275504A1./Cell Biol Toxicol. 2020 Jul 1. /Patent. US20190388398A1./SSRN. 2024 May 30.
References: [1]Jain MR, et al. Saroglitazar, a novel PPARα/γ agonist with predominant PPARα activity, shows lipid-lowering effects in preclinical models. Pharmacol Res Perspect. 2015 Jun;3(3):e00136.
CAS Number: 1639792-20-3
Molecular Weight: 901.42
Compound Purity: 98.85
Research Area: Metabolic Disease
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: PPAR