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SARS-CoV-2 Spike RBD E484K, N501Y (South Africa Variant Beta) Recombinant Protein
SARS-CoV-2 Spike RBD E484K, N501Y (South Africa Variant Beta) Recombinant Protein
Artikelnummer
AVIOPSN00006-100
Verpackungseinheit
100µg
Hersteller
Aviva Systems Biology
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Conjugation: Unconjugated.
Description: The SARS-CoV-2 Spike Receptor Binding Domain E484K, N501Y (South Africa Variant Beta) Recombinant Protein (OPSN00006) is expressed in Sf9 Baculovirus cells and includes a C-terminal Avidin-His Tag with purification via IMAC. The sequence includes amino acids 319-357 of the lineage B.1.351, 20H/501Y.V2 SARS-CoV-2 spike sequence first identified in South Africa. Suitable for Biotinylation and Protein:Protein Interaction assays in a variety of formats.
Description of Target: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The spike glycoprotein is found on the outside of the virus particle and gives coronavirus viruses their crown-like appearance. This glycoprotein mediates attachment of the virus particle and entry into the host cell. S protein is an important target for vaccine development, antibody therapies and diagnostic antigen-based tests.
Key Reference: Emergence and rapid spread of a new severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) lineage with multiple spike mutations in South Africa https://doi.org/10.1101/2020.12.21.20248640. Sci Rep. 2021 Apr 28;11(1):9166. doi: 10.1038/s41598-021-88696-5.
Molecular Weight: 30kDa.
Product Format: Liquid. 50 mM Tris-HCL, 1M NaCl, pH 7.5.
Protein Name: surface glycoprotein.
Protein Size: AA 319-537, E484K, N501Y (South Africa Variant Beta).
Purification: IMAC.
Purity: 0,9.
Tag: C-Avitag/His
Description: The SARS-CoV-2 Spike Receptor Binding Domain E484K, N501Y (South Africa Variant Beta) Recombinant Protein (OPSN00006) is expressed in Sf9 Baculovirus cells and includes a C-terminal Avidin-His Tag with purification via IMAC. The sequence includes amino acids 319-357 of the lineage B.1.351, 20H/501Y.V2 SARS-CoV-2 spike sequence first identified in South Africa. Suitable for Biotinylation and Protein:Protein Interaction assays in a variety of formats.
Description of Target: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The spike glycoprotein is found on the outside of the virus particle and gives coronavirus viruses their crown-like appearance. This glycoprotein mediates attachment of the virus particle and entry into the host cell. S protein is an important target for vaccine development, antibody therapies and diagnostic antigen-based tests.
Key Reference: Emergence and rapid spread of a new severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) lineage with multiple spike mutations in South Africa https://doi.org/10.1101/2020.12.21.20248640. Sci Rep. 2021 Apr 28;11(1):9166. doi: 10.1038/s41598-021-88696-5.
Molecular Weight: 30kDa.
Product Format: Liquid. 50 mM Tris-HCL, 1M NaCl, pH 7.5.
Protein Name: surface glycoprotein.
Protein Size: AA 319-537, E484K, N501Y (South Africa Variant Beta).
Purification: IMAC.
Purity: 0,9.
Tag: C-Avitag/His
| Artikelnummer | AVIOPSN00006-100 |
|---|---|
| Hersteller | Aviva Systems Biology |
| Hersteller Artikelnummer | OPSN00006-100 |
| Verpackungseinheit | 100µg |
| Mengeneinheit | STK |
| Reaktivität | SARS-Coronavirus |
| Methode | Functional Assay, In Vitro |
| Human Gene ID | 43740568 |
| Wirt | Baculovirus |
| Produktinformation (PDF) |
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| MSDS (PDF) |
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Immer für Sie da
Gernot Ensinger, M.Sc.
