Product Description: SB-706375 is an antagonist of the Urotensin II (UII) receptor. By blocking the Urotensin II receptor, SB-706375 reduces the kidney's response to UII and Urotensin-related peptide (URP) and significantly increases the Glomerular Filtration Rate (GFR). SB-706375 can be used in research on kidney diseases and hypertension[1].
Applications: Neuroscience-Neuromodulation
Formula: C20H22BrF3N2O5S
References: [1]Forty E J, et al. The urotensin system is up-regulated in the pre-hypertensive spontaneously hypertensive rat[J]. PLoS One, 2013, 8(12): e83317.
CAS Number: 733734-61-7
Molecular Weight: 539.36
Compound Purity: 99.08
Research Area: Cardiovascular Disease; Others
Target: Urotensin Receptor