Product Description: SB399885 is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with pKi values 9.11 and 9.02 for human recombinant and native 5-HT6 receptors, respectively. SB399885 has cognitive enhancing properties[1].
Applications: Neuroscience-Neuromodulation
Formula: C18H21Cl2N3O4S
References: [1]Warren D Hirst, et al. SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models. Eur J Pharmacol. 2006 Dec 28;553(1-3):109-19.
CAS Number: 402713-80-8
Molecular Weight: 446.35
Compound Purity: 98.85
Research Area: Neurological Disease
Solubility: DMSO : 4.17 mg/mL (ultrasonic;warming;heat to 60°C)
Target: 5-HT Receptor