SDZ NKT 343, CAS 180046-99-5

Product Description: SDZ NKT 343 is a selective, orally active NK1 receptor antagonist with an IC50 of 0.62 nM against human NK1 receptor. SDZ NKT 343 has good analgesic activity[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C33H33N5O5

References: [1]Walpole CS, et al. Comparative, general pharmacology of SDZ NKT 343, a novel, selective NK1 receptor antagonist. Br J Pharmacol. 1998 May;124(1):83-92. /[2]Walpole C, et al. 2-Nitrophenylcarbamoyl-(S)-prolyl-(S)-3-(2-naphthyl)alanyl-N-benzyl-N - methylamide (SDZ NKT 343), a potent human NK1 tachykinin receptor antagonist with good oral analgesic activity in chronic pain models. J Med Chem. 1998 Aug 13;41(17):3159-73.

CAS Number: 180046-99-5

Molecular Weight: 579.65

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Neurokinin Receptor

• Artikelnummer: MEXHY-108480-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-108480-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK