Simmitecan (hydrochloride), CAS 1247847-78-4

Product Description: Simmitecan hydrochloride, a 9-substituted lipophilic Camptothecin (HY-16560) derivative, is a potent topoisomerase I inhibitor. Simmitecan hydrochloride is an anticancer agent[1][2].

Applications: Cancer-programmed cell death

Formula: C34H39ClN4O6

References: [1]Rini B, et al. A phase I/II study of lenalidomide in combination with sunitinib in patients with advanced or metastatic renal cell carcinoma. Ann Oncol. 2014 Sep;25(9):1794-1799. /[2]Hu ZY, et al. Pharmacokinetic evaluation of the anticancer prodrug simmitecan in different experimental animals. Acta Pharmacol Sin. 2013 Nov;34(11):1437-48.

CAS Number: 1247847-78-4

Molecular Weight: 635.15

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Cytochrome P450;Topoisomerase

• Artikelnummer: MEXHY-107133-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-107133-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK