Skp2 inhibitor 3

Product Description: Skp2 inhibitor 3 (E35), an antitumor agent, is a potent S‑Phase Kinase-associated Protein 2 (SKP2) inhibitor, with an IC50 of 4.86 μM for Skp2-Cks1 binding. Skp2 inhibitor 3 (E35) significantly inhibits colony formation and migration, as well as arrests the cell cycle at the S-phase[1].

Formula: C21H19BrN4O2S

References: [1]Kaizhao Hu, et al. Discovery of Novel [1,2,4]Triazolo[1,5- a]pyrimidine Derivatives as Novel Potent S-Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer. J Med Chem. 2024 Sep 26;67(18):16435-16454.

Molecular Weight: 471.37

Compound Purity: 98.07

Research Area: Cancer

Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)

Target: E1/E2/E3 Enzyme

• Artikelnummer: MEXHY-162938-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-162938-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK