Product Description: SU-4313 is a potent protein tyrosine kinases (PTKs) modulator with IC50s of 14.5 μM, 18.8 μM, 11 μM, 16.9 μM, 8.0 μM for PDGFR, FLK-1, EGFR, HER2 Kinase and IGF-1R, respectively. SU-4313 has the potential for modulating tyrosine kinase signal transduction in order to regulate abnormal cell proliferation[1].
Applications: Cancer-Kinase/protease
Formula: C18H17NO
References: [1]Peng Cho Tang, et al. Indolinone compounds for the treatment of disease. WO1996040116A1.
CAS Number: 186611-55-2
Molecular Weight: 263.33
Compound Purity: 99.31
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: EGFR;IGF-1R;PDGFR