Product Description: TFCP2L1-IN-1 is a specific small molecule targeting TFCP2L1’s active domain with anti-cancer activity. TFCP2L1-IN-1 synergizes with Sorafenib (HY-10201) to induce Apoptosis and reduces cell proliferation, invasion, metastasis, clonal formation and sphere-forming capacity in hepatocellular carcinoma cells[1].
Applications: Cancer-programmed cell death
Formula: C15H13BrN2OS
References: [1]Qiu D, et al. TFCP2L1 drives stemness and enhances their resistance to Sorafenib treatment by modulating the NANOG/STAT3 pathway in hepatocellular carcinoma. Oncogenesis. 2024 Sep 12;13(1):33.
CAS Number: 364621-46-5
Molecular Weight: 349.25
Compound Purity: 99.66
Research Area: Cancer
Solubility: DMSO : 175 mg/mL (ultrasonic)
Target: Apoptosis